Surgical management of parathyroid diseases: a single-center experience with different technological resources

Abstract

Background: Hyperparathyroidism (HPT) is an endocrine disorder that can lead to significant complications, including impaired calcium and phosphorus metabolism, with consequences on cardiovascular, bone, and renal health.
Objective: The aim of this study was to describe the short- and mid-term results of surgical treatment in patients undergoing surgery due to PHPT, SHPT and THPT.
Material and methods: We conducted a retrospective and observational cohort study. Material and methods: The clinical records of patients undergoing surgery between January 2018 and April 2025 were reviewed. The variables analyzed included the number of patients, demographic characteristics, types of diseases, surgical techniques, complications, and short- and mid-term follow-up. The standard reference values for the biochemical tests of the institutional laboratory were considered.
Results: A total of 37 cases were included; 29 patients with PHPT (78.4%), 7 with SHPT (18.9%), and 1 with THPT (2.7%). Fifteen patients underwent bilateral neck exploration, 11 patients underwent minimally invasive neck exploration, and 11 patients underwent transoral endoscopic parathyroidectomy via a vestibular approach (TOEPVA). Five patients (13.5%) presented hypocalcemia and 3 (8.1%) developed temporary dysphonia. There were no surgical site infections. Serum calcium levels normalized in 86.5% of patients within 30 days of surgery.
Conclusion: The utilization of the aforementioned techniques in the series presented did not result in significant complications with surgical treatment and facilitated the normalization of calcemia in the majority of cases.