Comparison of the prevalence of blood group A in gastric cancer patients and blood donors

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Daniel González González
Gabriela Wagner
Leandro Telles
Luis Ruso

Abstract

Background: Gastric cancer has high incidence and mortality in Uruguay. Blood group A has been considered a risk factor for gastric cancer and has high prevalence in this disease.
Objective: The aim of this study is to compare the percentage of blood group A in patients with gastric cancer and in blood donors in Uruguay.
Material and methods: We conducted an observational and retrospective study. We used the sample size calculation for comparing proportions with a confidence of 95% and 80% power. The number calculated was 149 for each group. We included all the patients from Hospital Maciel and Cooperativa Médica de Florida who met the admission criteria and a population of blood donors from both institutions. The chi-square test was used and a p value < 0.05 was considered statistically significant.
Results: A total of 153 patients and blood donors were included in each group. Blood group A was less common in gastric cancer patients than in blood donors (35.9% vs. 36.6%). The difference was not statistically significant between the groups studied.
Conclusions: We did not find any significant difference in the percentage of blood group A in the groups compared.

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How to Cite
González González, D., Wagner, G., Telles, L., & Ruso, L. (2022). Comparison of the prevalence of blood group A in gastric cancer patients and blood donors. Revista Argentina De Cirugía, 114(2), 117–123. Retrieved from https://revista.aac.org.ar/index.php/RevArgentCirug/article/view/544
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Original Article