What should I ask myself before starting research on human subjects?

Abstract

In a text that is now part of the classic literature on ethics, Ezekiel Emanuel states:
“Why does clinical research, meaning on human subjects, need special ethical requirements?
Why is it that good scientific research alone is not enough? Is good science not equivalent to good ethics? These are common questions, especially for clinical researchers. (Note that clinical research refers to research on human subjects, whatever it may be,
including surgical research).