Laboratory studies as a tool for the differential diagnosis between acute appendicitis and lymphoid hyperplasia

Main Article Content

Héctor H. Romero Garza
Patricia E. Oviedo Aguilar
Patsy A. Morales González
Carlos A. de la Cruz de la Cruz
Gerardo E. Muñoz Maldonado


Background: Acute appendicitis (AA) is one of the main surgical pathologies in our country and worldwide. Despite being a surgery that is frequently done, it is still reported a 10-20% of negative appendectomies (NA).
Objective: The objective of the study is to compare clinical, laboratory and radiology results with the histopathology diagnosis.
Material and methods: A retrospective study was done analyzing the data of patients with clinical diagnosis of AA from February 2013 to December 2017, in a tertiary hospital in Monterrey, Mexico.
They were classified by their histopathological results into different groups: AA or NA; and the AA was subdivided into complicated AA and uncomplicated AA. Finally, these groups were also subdivided by ages, into pediatric and adult groups of each category. A descriptive analysis was made using frequencies, percentages, median and the interquartile range. Laboratory results were compared with
the Mann-Whitney test. Considering a p-value of p < 0.05 as statistically significant.
Results: In our group of patients both genders had AA in a similar frequency, the time between the appearance of symptoms and reaching for medical advice was an important factor for having complicated AA. There is a correlation between leukocytosis, neutrophil count and platelet count elevated in presence of AA against NA.
Conclusion: Laboratory studies did not report significant changes in pediatric patients with AA. In adults with uncomplicated AA vs. complicated AA, white blood cell count, and neutrophil count are statistically significant.


Download data is not yet available.

Article Details

How to Cite
Romero Garza, H. H., Oviedo Aguilar, P. E., Morales González, P. A., de la Cruz de la Cruz, C. A., & Muñoz Maldonado, G. E. (2021). Laboratory studies as a tool for the differential diagnosis between acute appendicitis and lymphoid hyperplasia. Revista Argentina De Cirugía, 112(4), 517–525. (Original work published March 16, 2021)
Original Article

Most read articles by the same author(s)